Statins (used to lower cholesterol) use does not reduce the risk of heart attacks

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In a recent study no connection was found between the level of exposition to statins in the population and the incidence or mortality from heart attack (Nilsson et al 2011). The use rate of statins increased almost three times for both men and women between 1998 and 2002. However, the change in statin use from 1998 to 2000 showed no correlation to the change in heart attack mortality. They concluded, “despite a widespread and increasing utilisation of statins, no correlation to the incidence or mortality of AMI (heart attack) could be detected.”  It should be highlighted that all these researchers are medical doctors or working in a medical establishment.

The drugs don’t work but have serious side effects including recent studies showing increases in diabetes and breast cancer.  Although there are many more serous side effects.

In one study Atorvastatin (a statin drug used to lower cholesterol) increases the risk for new-onset type 2 diabetes, according to an analysis of three large trials published in the Journal of the American College of Cardiology. (The trials, as well as this analysis, were sponsored by atorvastatin's manufacturer). Researchers were responding to a 2010 Lancet meta-analysis, which found an increased risk for new-onset diabetes after all statin use and were trying to show their drug was not so bad. In the meta analysis released in the Lancet, using data from 13 randomized trials comprising some 90,000 subjects, found a 9% increase in diabetes risk among those receiving statins compared with controls. The statin-diabetes association was stronger with increasing age and given these drugs are give to older people this is of even more concern. The authors calculate that 255 patients would have to be treated with statins for 4 years to produce an additional case of diabetes. This compares to the need to treat around 300 people with statin drugs to reduce the risk of heart attack (not death) by one or according to the research above no reduction at all.  However, the medical profession continue to use relative statistics and say they benefit by 30 or more percent. Obviously these doctors failed stats at university or more likely did not do them.

A recent study (McDougall et al September 2013) found current users of statins for 10 years or longer had a 1.83-to 1.97-fold increased respectively for Ductal and Lobular Breast Cancer. In their conclusion they reported that long-term use of statins was associated with increased risks of both IDC and ILC.

In support of t is here is a comment from one of my readers that might interest you.

“I recently stopped my statin drugs as I was experiencing bad muscle pains. My GP actually said that "statins don't really help women anyway". Hello, why has he then prescribed this and wasted all my money? “ GD, Brisbane

Diet, Not Drugs

As a society we spend so much money that is absolutely wasted on medication. The disease is not high cholesterol or even obesity. The disease is our diet and our lifestyle. When we address these issues then all the symptoms, yes - all, disappear and we can lead a healthy long life. 

A recent randomized controlled study (NORDIET) on 88 mildly people with elevated cholesterol showed how simple the solution is. 1One group had a diet rich in high-fibre plant foods: fruits, berries, vegetables, whole grains, grapeseed oil, nuts, fish and low-fat milk products, but low in salt, added sugars and saturated fats. The other group had the average western processed diet. Compared with controls, those on the healthy Nordic diet (ND. similar to the Mediterranean diet) had a decrease in plasma cholesterol, LDL cholesterol, high-density lipoprotein (HDL) cholesterol, LDL/HDL and apolipoprotein (apo)B/apoA1. The ND also had reduced insulin and systolic BP by compared with the control diet. Body weight decreased after 6 weeks in the ND compared with the control group. The conclusions after 6 weeks in the study was that a healthy ND improves blood lipid profile and insulin sensitivity and lowers blood pressure at clinically relevant levels in people with elevated cholesterol without any medication. 

While cholesterol is not a health problem it is an indicator of poor health, primarily stress on the liver and growing research is also showing that cholesterol may actually be protective. 

A study of 6984 patients aged 65 years or older found mortality was inversely related to cholesterol levels. That is low cholesterol levels were associated with in-hospital mortality 2. The study concluded that among older hospitalized adults, low serum cholesterol levels appear to be an independent predictor of short-term mortality.  

In another study of more than 52,000 Norwegians over a 10-year period the overall risk of death was the same in men with cholesterol levels of 7.0 mmol/l or higher than in individuals with levels of less than 5.0 mmol 3. In the individuals with cholesterol levels in the 5.0 – 5.9 mmol/l the risk of death was 23 per cent lower than in men with the lowest cholesterol levels. In women, the higher the cholesterol level the lower the overall risk of death. The third study of 82,000 adults in the UK over 8 years again found that higher total cholesterol levels were actually associated with a reduced risk of death due to stroke and that higher cholesterol levels are not a risk factor for heart disease 4.  

There is no valid reason to focus on lowering cholesterol and especially no valid reason to take statin medication which has serious side effects, when the solution really is so simple.  

References: 

1 

Adamsson, et al 2011. Effects of a healthy Nordic diet on cardiovascular risk factors in hypercholesterolaemic subjects: a randomized controlled trial (NORDIET). 

DOI: 10.1111/j.1365-2796.2010.02290.Journal of Internal Medicine 

Volume 269, Issue 2, pages 150–159, February 2011 

2 

Onder G, Landi F, Volpato S, Fellin R, Carbonin P, Gambassi G, Bernabei R  

The American Journal of Medicine [2003, 115(4):265-271]  

DOI: 10.1016/S0002-9343(03)00354-1  

3 

Petursson H, et al. Is the use of cholesterol in mortality risk algorithms in clinical guidelines valid? Ten years prospective data from the Norwegian HUNT 2 study. J Eval Clin Pract. 25 Sept 2011 [Epub ahead of print] 

4 

Hamer M, et al. Comparison of risk factors for fatal stroke and ischemic heart disease: A prospective follow up of the health survey for England. Atherosclerosis epub 22 August 2011.